Robitussin does what??

1 December 2007 at 10:13 am 1 comment

A study published in Fertility and Sterlity in 1982 involved treatment of 40 women who had been unable to conceive for at least 10 months, due to hostile cervical mucus. They took 200 mg of guaifenesin (Robitussin, Tussin), three times daily, from cycle day 5 until ovulation was observed based on rise in basal body temperature.

75% of the women had an improvement in the quality of cervical mucus (improved spinnbarkeit and ferning). Of the 23 women with marked improvement, 15 of them became pregnant, after an average of 2.4 months.

Guaifenesin is typically used to increase respiratory tract secretions, and a similar mechanism is believed to occur, improving cervical mucus.

Patients that had NO cervical mucus to begin with were excluded from the study.

Subsequent studies and reviews have concluded that while treatment with guaifenesin is the simplest and cheapest way to improve mucus quality, it is also the least effective. For true cervical factor infertility, ethyinyl estradiol (synthetic estrogen) may be prescribed.

NOTE: Guaifenesin alone should be taken (original Robitussin, Tussin, etc.) Many cold medications contain multiple active drugs, most of which are unsafe during pregnancy or have other side effects. For example, Robitussin-DM contains dextromethorphan.

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Entry filed under: Drugs, Female Infertility. Tags: , , , , , , .

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